Blood Clotting Essay

Coagulation, or thrombogenesis, is the accomplish by which squanderer choke offs in an attempt to restrict blood handout from an soil site, and repair the damaged vas. Most of the time clabberting is a good thing, however there atomic number 18 circumstances when a clot can form abnormally, leading to heart attack, stroke, or some other right medical problems. A blood clot forms almost immediately later on the bleeding occurs, which is possible through enzymes and other substances in blood that oppose to breaks in vessel walls. The clot is a temporary fix forestalling move on blood loss. There are four major parts of blood clot formation. The first step in coagulation is the formation of the thrombocyte plug. Platelets are the smallest of the three major types of blood cells whose primary function is to prevent bleeding.When encountering a damaged blood vessel, the blood platelets become stimulated and rush to the injury site where they clump in concert, forming a plu g and restricting the bleeding. They also chuck out substances to begin the chemical reception of the clotting process. These chemical reactions are responsible for(p) for growing the blood clot. Dissolved proteins, also referred to as clotting factors, are contained within the blood for the purpose of promoting blood clots. These proteins send signals to each other and enhance each others activity exponentially at the site of injury, resulting in a rapid chemical chain reaction which produces fibrin, the main protein forming clots. This blood clot formed with fibrin is tougher and more durable than the platelet plug.Once the blood clot forms, it is important that it not grow and dust to the rest of the body, which can cause serious damage. This is where anti-clotting comes in to play. Proteins such as antithrombin, protein C, and protein S, are known anti-clotting proteins and exist in a natural ease with the clotting factors. These substances work to neutralize excess clottin g factors, preventing the clot from press release to places it should not. The final part of the process is where the clot is slowly broken land by the body. Once the damaged tissue heals, the body gradually degrades the clot and reabsorbs it. The tough fibrin strands in a blood clot are fade away by an enzyme called plasmin. Plasmin is activated by other substances working together to help the clot break down.The whole process of blood clotting is whenever the blood is exposed to certain substances. These are known as thrombogenic substances because they grow the formation of thrombus (clot). Many of these substances, such as tissue factor, collagen, and von Willebrand factor, are located in the skin or in the blood vessel walls, typically separated from flowing blood. If they come into contact with flowing blood, this typically means the blood vessel wall is ruptured and bleeding. A clot may also form when blood is not flowing properly. http//www.hematology.org/patients/blood -disorders/blood-clots/5233.aspx http//www.webmd.com/a-to-z-guides/blood-clots